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Conclusion The question "is glutathione anti-inflammatory" reveals a fundamental truth about our health: the better we protect our cells from oxidative stress, the better our body can manage its natural inflammatory response

Oestrogen leads to Histamine release, that leads to recirculating oestrogen etc

10.1038/s41467-024-48695-2 113 WuJ.QiaoS.XiangY.CuiM.YaoX.LinR.et al (2021)